- Author: Hwa Jin Cho, Kook Joo Na, Do Wan Kim, Young Earl Choi, Jae Sook Ma, In Seok Jeong
- Date: 2014/06/01
- Journal: European journal of pediatrics;173;823-826
- PMID:
- PMCID: 24573572
- DOI: 10.1007/s00431-014-2283-9
Abstract
Congenital chylothorax is a rare condition, but it is the most common cause of pleural effusion in neonates and infants. Here, we report on the first trials of the intrapleural instillation of an extract of Viscum album (European mistletoe) (Abnobaviscum Q®) in two infants with congenital chylothorax that was refractory to standard conservative management and thoracic duct ligation.
Conclusion: The clinical course of both children improved with no side effects related to the extract after following up the children for 2 years and 9 months, respectively. Randomized multicenter prospective studies will help determine the effectiveness of pleurodesis with a V. album extract and the occurrence of long-term side effects with this agent.